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Study shows safe and effective removal of age spots in darker skin types

A novel dual-wavelength, dual pulse duration laser was evaluated for use on solar lentigines in Asian patients with results showing 90% of patients achieved moderate to significant improvement.

By Emilee Green | Jun 19, 2019

chan-june-editorschoice-cropWausau, WI (June 19, 2019) – Laser therapy for solar lentigines is growing in popularity with less downtime and complications in comparison to topical and physical therapies. In this study, 20 Asian subjects were treated with the novel dual-wavelength, dual-pulse duration picosecond laser. Treatment sessions involving the pigmented lesion were repeated up to 3 laser sessions 4-6 weeks apart depending on their clinical response.

The clinical report of this study, published in Lasers in Surgery and Medicine (LSM), the official journal of the American Society for Laser Medicine and Surgery, Inc. (ASLMS), was selected as the June 2019 Editor’s Choice.

The study, led by Henry Chan, MD, PhD, FRCP is titled “A Prospective Study in the Treatment of Lentigines in Asian Skin Using 532 nm Picosecond Nd:YAG Laser.”

“This work further illustrates the use of picosecond laser to treat lentigines, a most common condition among Asians. While it is effective, risk of post-inflammatory hyperpigmentation remains to be an issue and due to climate difference, it is higher than previously reported,” said Chan.

Outcome measurements included 5-grade Physician’s Global Assessment (PGA) score, the improvement rate of relative Melanin index, subjective measures of pain and overall patient satisfaction. The efficacy was studied, and any adverse effects were recorded. It was shown that the novel dual-wavelength, dual-pulse duration laser for removal of solar lentigines in darker skin type appears to be safe and effective.

Dr. Henry Chan is a specialist in dermatology. He is also currently the Honorary Clinical Professor of the Division of Dermatology, Department of Medicine, The University of Hong Kong; Honorary Consultant Dermatologist of Queen Mary Hospital, Hong Kong and Visiting Scientist (research staff) of the Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, USA. He is a council and court member of the University of Hong Kong. He is the Associate Editor of Lasers in Surgery and Medicine and serves on the editorial board of other international journals including the Dermatologic Surgery, Lasers in Medical Science, Journal of Cosmetic and Laser Therapy and Archives of Dermatological Research.

Editor’s Choice is an exclusive article published in LSM, the official journal of the ASLMS. View the complete manuscript.

The American Society for Laser Medicine and Surgery, Inc. (ASLMS) is the largest multi-disciplinary professional organization, dedicated to the development and application of lasers and related technology for health care applications. ASLMS promotes excellence in patient care by advancing biomedical application of lasers and other related technologies worldwide. ASLMS membership includes physicians and surgeons representing multiple specialties, physicists involved in product development, biomedical engineers, biologists, nurses, industry representatives and manufacturers. For more information, visit

The American Society for Laser Medicine and Surgery is the world’s largest scientific organization dedicated to promoting research, education and high standards of clinical care in the field of medical laser applications. It provides a forum for the exchange of scientific information and participation in communicating the latest developments in laser medicine and surgery to clinicians, research investigators, government and regulatory agencies, and the public.

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